Both the extracts exhibited a significant antibacterial activity against all the screened microorganisms. Key words: Leucas aspera, Antibacterial activity. Leucas aspera, Leucas zeylanica, antifungal, dermatophytes. RESULTS: Antifungal activity of Leucas sp. against Dermatophytes. Objective: The aim of this study was to explicate antibacterial, antifungal, and antioxidant activities of Leucas aspera flowers. Methods: Antibacterial activity was.

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The medicinal properties of plant species have made an outstanding contribution to the origin and evolution of many traditional herbal therapies. Some tribal medicinal plants of Chittagong hill tracts, Bangladesh.

Materials and methods 2. The activity may be due to their hydrophobic action which is responsible for the breakage of lipid bilayer of the cell membrane, leading to losing its permeability and a subsequent leakage of its cell contents E, Adenipekun E, Coker H.

Several phytochemical surveys have been published, including the random sampling approach which involved some plant accessions collected from all parts of the world. It may be attributed to the fact that the plant extracts being in crude form contain a smaller concentrations of bioactive compounds [18].

Enter the email address you signed up with and we’ll email you a reset link. Article Information Sr No: Int J Pharm Sci Res ; 7 2: Antifungal activity of three Chilean plant extracts on Botrytis cinerea. In addition, this study also evaluated the antibacterial activity of different parts of L.

Purification and identification of active antibacterial components in Carpobrotus edulis L. U and Begum J. Antifungal effects of Melaleuca alterniflia tea tree oil and its components on Candida albicans, Candida glabrata and Saccharomyces cerevisiae. London, Butter Worths and Co.

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The increase in resistance of microorganisms encouraged scientists to search for new antimicrobial agents from plants. The results for leuas free radical scavenging of all the plant extracts and known antioxidants were presented in Figure 1. In classifying the antimicrobial activity it would be generally expected that much greater number would be active against Gram positive than Gram negative bacteria [19]. Phytochemical screening and antimicrobial activity of Leucas marrubioides desf.


In this study, leucss well diffusion method was used to determine the susceptibilities of dermatophytes to methanol extracts of both the plants.

The antifungal activity of plants extract was given in the Table 1. Thrombolytic activities of Spilanthescalva and Leucas zeylanica. In general, the mean zone of inhibition produced by the commercial antibiotic, activitu, was between This plant has a history of used for the treatment of various ailments and the most commonly used plant part for this purpose is leaves and roots.

Similarly the study performed by 13 showed the antifungal activity of ethanol and methanol extract of Spilanthes paniculata against Aspergillusniger, at the same time it is also stated in the above study that ethyl acetate extract of Leucas aspera also showed the antifungal effect against Aspergillusniger, where as in this experiment methanol extract of leaf of Leucas aspera and Leucas zeylanica exhibited antfungal activity against Aspergillus aspefa which is reported for the first time.

Skip to main content. In the previous investigation Gandhiraja et al. The activity against both types of bacteria may be indicative of the presence of broad spectrum of antibiotic compounds or simply general metabolic toxin [20]. Infect Control Hosp Epidemiol leuczs Preparation of extract The leaves and pf were washed and extracted with acetone, ethyl acetate and chloroform for 48 hours with occasional shaking in a beaker.

The experiment was conducted in triplicates. Antimicrobial and antioxidant flavonoids from the root wood of Bolusanthus speciosus. Given the results discussed above, it becomes evident that methanolic extracts considered for the study is found to posses antifungal activity and can be considered for further investigation with minimal side effects in humans.


Ahmed I, Beg A.

The difference of the result may be due to the different solvent used for the extraction and also the fact of using lf plant and part of the plant. Conflict of interest statement: Table 1 Antibacterial activity zone of inhibition of different parts root, flower, leaf and stem of L.

Antioxidant and antibacterial activity of different parts of Leucas aspera

From the case it is evident that all the studied pathogens were found to be susceptible to methanol extract of Leucas aspera while only axpera pathogens were susceptible to Leucas zeylanica. Overall reports antimicrobil that this antimicrobial mechanism involves damage of membrane and our results further authenticate sntimicrobial phytochemicals extracts of medicinal plants compromises the structural and functional integrity of cytoplasmic membranes.

Thus, the root was chosen for further determination of the IC 50 value. This revival of interest in plant-derived drugs is mainly due to the current widespread belief that green medicine is safe and more dependable than the costly synthetic drug, many of which may have adverse side effects [2].

Methanol extract of root possessed antioxidant activity near the range of vitamin E and thus could be a potential rich source of natural antioxidant. The Flora of British India. The results showed that L. Traditionally, the whole plant is taken orally for analgesic, antipyretic, antirheumatic, anti-inflammatory and antibacterial treatment and its paste is applied topically to inflamed areas [5].

A review of the literature. Asian Pac J Trop Biomed. Two commonly used medicinal plants Leucas aspera and Leucas zeylanica were investigated for their biological potentials. Since the root exhibited the highest antioxidant activity, the root was further analyzed against the Antimicrlbial free radical.

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